ScienceDaily (Aug. 30, 2012) ? Researchers at USC have devised a method for detecting certain neurological disorders through the study of eye movements.
In a study published August 30 in the Journal of Neurology, researchers claim that because Attention Deficit Hyperactivity Disorder (ADHD), Fetal Alcohol Spectrum Disorder (FASD) and Parkinson's Disease each involve ocular control and attention dysfunctions, they can be easily identified through an evaluation of how patients move their eyes while they watch television.
"Natural attention and eye movement behavior -- like a drop of saliva -- contains a biometric signature of an individual and her/his state of brain function or dysfunction," the article states. "Such individual signatures, and especially potential biomarkers of particular neurological disorders which they may contain, however, have not yet been successfully decoded."
Typical methods of detection -- clinical evaluation, structured behavioral tasks and neuroimaging -- are costly, labor-intensive and limited by a patient's ability to understand and comply with instructions.
To solve this problem, doctoral student Po-He Tseng and Professor Laurent Itti of the Department of Computer Science at the USC Viterbi School of Engineering, along with collaborators at Queen's University in Canada, have devised a new screening method.
Participants in the study were simply instructed to "watch and enjoy" television clips for 20 minutes while their eye movements were recorded. Eye-tracking data was then combined with normative eye-tracking data and a computational model of visual attention to extract 224 quantitative features, allowing the team to use new machine-learning techniques to identify critical features that differentiated patients from control subjects.
With eye movement data from 108 subjects, the team was able to identify older adults with Parkinson's Disease with 89.6 percent accuracy, and children with either ADHD or FASD with 77.3 percent accuracy.
Providing new insights into which aspects of attention and gaze control are affected by specific disorders, the team's method provides considerable promise as an easily deployed, low-cost, high-throughput screening tool, especially for young children and elderly populations who may be less compliant to traditional tests.
"For the first time, we can actually decode a person's neurological state from their everyday behavior, without having to subject them to difficult or time-consuming tests," Itti said.
Funding for the research came from the National Science Foundation, the Army Research Office, the Human Frontier Science Program and the Canadian Institutes of Health Research.
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The above story is reprinted from materials provided by University of Southern California. The original article was written by Katie Dunham.
Note: Materials may be edited for content and length. For further information, please contact the source cited above.
Journal Reference:
- Po-He Tseng, Ian G. M. Cameron, Giovanna Pari, James N. Reynolds, Douglas P. Munoz, Laurent Itti. High-throughput classification of clinical populations from natural viewing eye movements. Journal of Neurology, 2012; DOI: 10.1007/s00415-012-6631-2
Note: If no author is given, the source is cited instead.
Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.
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September 01, 2012
September is National Preparedness Month, and veterinarians are encouraged to do their part to help clients and community members learn about hazards and what to do with their pets, horses, or livestock in an emergency.